Clk4 Antibody - N-terminal region
Artikelnummer:
ASB-ARP30646_P050
- Bilder (3)
| Artikelname: | Clk4 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP30646_P050 |
| Hersteller Artikelnummer: | ARP30646_P050 |
| Alternativnummer: | ASB-ARP30646_P050-25UL,ASB-ARP30646_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Alternative Synonym: | C85119, AI987988 |
| Clk4 is a dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Clk4 phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Clk4 phosphorylates SRSF1 and SRSF3. Clk4 is required for the regulation of alternative splicing of MAPT/TAU. Clk4 regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. |
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Host: Rabbit Target Name: Clk4 Antibody Dilution: 0.25ug/ml Sample Type: Mouse Pancreas |
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Surface Plasmon Resonance Kinetic Characterization of Polyclonal Antibody Affinity. Purified polyclonal antibodies were immobilized on a Protein A/G coated Carterra LSA sensor chip (PAGH200M) at concentrations of 5, and 50 ug/mL in duplicate. Antibodies on the surface were exposed to interaction with peptides sequentially via microfluidic controlled flow at 333nM peptide concentration for kinetic characterization of the binders for affinity and specificity, followed by curve fitting using the Kinetics software. Kd determinations for both concentrations were averaged and results and standard deviation are shown. |
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Clk4 antibody - N-terminal region (ARP30646_P050) in Mouse Pancreas using Western Blot |
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