PHOX2A Antibody - N-terminal region
Artikelnummer:
ASB-ARP31726_P050
- Bilder (3)
| Artikelname: | PHOX2A Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP31726_P050 |
| Hersteller Artikelnummer: | ARP31726_P050 |
| Alternativnummer: | ASB-ARP31726_P050-25UL,ASB-ARP31726_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human PHOX2A |
| Alternative Synonym: | ARIX, FEOM2, NCAM2, PMX2A, CFEOM2 |
| PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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Immunohistochemistry with Testis tissue at an antibody concentration of 5ug/ml using anti-PHOX2A antibody (ARP31726_P050) |
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WB Suggested Anti-PHOX2A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysatePHOX2A is supported by BioGPS gene expression data to be expressed in 721_B |
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PHOX2A antibody - N-terminal region (ARP31726_P050) in Human 721_B using Western Blot |
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