PHOX2A Antibody - N-terminal region

Catalog Number: ASB-ARP31726_P050
Article Name: PHOX2A Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP31726_P050
Supplier Catalog Number: ARP31726_P050
Alternative Catalog Number: ASB-ARP31726_P050-25UL,ASB-ARP31726_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHOX2A
Alternative Names: ARIX, FEOM2, NCAM2, PMX2A, CFEOM2
PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 30kDa
NCBI: 401
UniProt: O14813
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunohistochemistry with Testis tissue at an antibody concentration of 5ug/ml using anti-PHOX2A antibody (ARP31726_P050)
WB Suggested Anti-PHOX2A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysatePHOX2A is supported by BioGPS gene expression data to be expressed in 721_B
PHOX2A antibody - N-terminal region (ARP31726_P050) in Human 721_B using Western Blot