ZFPM1 Antibody - middle region

Artikelnummer: ASB-ARP32193_P050
Artikelname: ZFPM1 Antibody - middle region
Artikelnummer: ASB-ARP32193_P050
Hersteller Artikelnummer: ARP32193_P050
Alternativnummer: ASB-ARP32193_P050-25UL,ASB-ARP32193_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Human, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZFPM1
Alternative Synonym: FOG, FOG1, ZNF408, ZNF89A, ZC2HC11A
ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 105kDa
NCBI: 161882
UniProt: Q8IX07
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-ZFPM1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle
Host: Rabbit
Target: ZFPM1
Positive control (+): Mouse spleen (M-SP)
Negative control (-): Mouse intestine (M-IN)
Antibody concentration: 1ug/mg
ZFPM1 antibody - middle region (ARP32193_P050) in Human Muscle using Western Blot