ZFPM1 Antibody - middle region
Catalog Number:
ASB-ARP32193_P050
- Images (3)
| Article Name: | ZFPM1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP32193_P050 |
| Supplier Catalog Number: | ARP32193_P050 |
| Alternative Catalog Number: | ASB-ARP32193_P050-25UL,ASB-ARP32193_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Human, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human ZFPM1 |
| Alternative Names: | FOG, FOG1, ZNF408, ZNF89A, ZC2HC11A |
| ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. ZFPM1 may be involved in regulation of some genes in gonads. ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2. |
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WB Suggested Anti-ZFPM1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Human Muscle |
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Host: Rabbit Target: ZFPM1 Positive control (+): Mouse spleen (M-SP) Negative control (-): Mouse intestine (M-IN) Antibody concentration: 1ug/mg |
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ZFPM1 antibody - middle region (ARP32193_P050) in Human Muscle using Western Blot |
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