COPS5 Antibody - N-terminal region
Artikelnummer:
ASB-ARP32834_P050
- Bilder (3)
| Artikelname: | COPS5 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP32834_P050 |
| Hersteller Artikelnummer: | ARP32834_P050 |
| Alternativnummer: | ASB-ARP32834_P050-25UL,ASB-ARP32834_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human COPS5 |
| Alternative Synonym: | CSN5, JAB1, SGN5, MOV-34 |
| The protein encoded by COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. |
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Human Heart |
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WB Suggested Anti-COPS5 Antibody Titration: 0.2-1 ug/ml Positive Control: HepG2 cell lysate |
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COPS5 antibody - N-terminal region (ARP32834_P050) in Human HepG2 using Western Blot |
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