COPS5 Antibody - N-terminal region

Catalog Number: ASB-ARP32834_P050
Article Name: COPS5 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP32834_P050
Supplier Catalog Number: ARP32834_P050
Alternative Catalog Number: ASB-ARP32834_P050-25UL,ASB-ARP32834_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Human
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COPS5
Alternative Names: CSN5, JAB1, SGN5, MOV-34
The protein encoded by COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 38kDa
NCBI: 10987
UniProt: Q92905
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Heart
WB Suggested Anti-COPS5 Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
COPS5 antibody - N-terminal region (ARP32834_P050) in Human HepG2 using Western Blot