GJB2 Antibody - middle region

Artikelnummer: ASB-ARP36608_T100
Artikelname: GJB2 Antibody - middle region
Artikelnummer: ASB-ARP36608_T100
Hersteller Artikelnummer: ARP36608_T100
Alternativnummer: ASB-ARP36608_T100-25UL,ASB-ARP36608_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GJB2
Alternative Synonym: HID, KID, PPK, BAPS, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A
Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1, MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 25kDa
NCBI: 2706
UniProt: P29033
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-GJB2 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Human Lung
WB Suggested Anti-GJB2 Antibody
Positive Control: Lane 1: 4ug mCx26 elution fraction 6 Lane 2: 4ug mCx26 elution fraction 7Lane 3: 4ug mCx26 elution fraction 6 + other Cx26 antibody Lane 4: 4ug mCx26 elution fraction 7 + other Cx26 antibody
Primary Antibody Dilution : 1:3000
Secondary Antibody : Anti-rabbit-HRP
Secondry Antibody Dilution : 1:3000
Submitted by: Juan Zou, Georgia state unviersity
GJB2 antibody - N-terminal region (ARP36608_T100) in Human Lung using Western Blot