GJB2 Antibody - middle region

Catalog Number: ASB-ARP36608_T100
Article Name: GJB2 Antibody - middle region
Biozol Catalog Number: ASB-ARP36608_T100
Supplier Catalog Number: ARP36608_T100
Alternative Catalog Number: ASB-ARP36608_T100-25UL,ASB-ARP36608_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GJB2
Alternative Names: HID, KID, PPK, BAPS, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A
Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1, MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 25kDa
NCBI: 2706
UniProt: P29033
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-GJB2 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:62500
Positive Control: Human Lung
WB Suggested Anti-GJB2 Antibody
Positive Control: Lane 1: 4ug mCx26 elution fraction 6 Lane 2: 4ug mCx26 elution fraction 7Lane 3: 4ug mCx26 elution fraction 6 + other Cx26 antibody Lane 4: 4ug mCx26 elution fraction 7 + other Cx26 antibody
Primary Antibody Dilution : 1:3000
Secondary Antibody : Anti-rabbit-HRP
Secondry Antibody Dilution : 1:3000
Submitted by: Juan Zou, Georgia state unviersity
GJB2 antibody - N-terminal region (ARP36608_T100) in Human Lung using Western Blot