SSX2 Antibody - C-terminal region
Artikelnummer:
ASB-ARP37719_P050
- Bilder (3)
| Artikelname: | SSX2 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP37719_P050 |
| Hersteller Artikelnummer: | ARP37719_P050 |
| Alternativnummer: | ASB-ARP37719_P050-25UL,ASB-ARP37719_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human SSX2 |
| Alternative Synonym: | SSX, HD21, CT5.2, CT5.2A, HOM-MEL-40 |
| SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. |
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WB Suggested Anti-SSX2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Jurkat cell lysate |
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Host: Rabbit Target Name: SSX2 Sample Tissue: Human Jurkat Antibody Dilution: 1.0ug/ml |
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SSX2 antibody - C-terminal region (ARP37719_P050) in Human Jurkat using Western Blot |
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