SSX2 Antibody - C-terminal region

Catalog Number: ASB-ARP37719_P050
Article Name: SSX2 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP37719_P050
Supplier Catalog Number: ARP37719_P050
Alternative Catalog Number: ASB-ARP37719_P050-25UL,ASB-ARP37719_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Human
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SSX2
Alternative Names: SSX, HD21, CT5.2, CT5.2A, HOM-MEL-40
SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 25kDa
NCBI: 6757
UniProt: Q16385-2
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-SSX2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
Host: Rabbit
Target Name: SSX2
Sample Tissue: Human Jurkat
Antibody Dilution: 1.0ug/ml
SSX2 antibody - C-terminal region (ARP37719_P050) in Human Jurkat using Western Blot