Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of human UTX
Alternative Synonym:
UTX, KABUK2, bA386N14.2
UTX is a histone demethylase that specifically demethylates Lys-27 of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 Lys-27. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of Lys-27 of histone H3 is concomitent with methylation of Lys-4 of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-UTX Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: MCF7 cell lysateKDM6A is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells
Host: Rabbit Target: KDM6A Positive control (+): Human Ovary (OV) Negative control (-): Human liver (LI) Antibody concentration: 1ug/ml
UTX antibody - middle region (ARP39483_P050) in Human MCF7 using Western Blot
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