UTX Antibody - C-terminal region

Artikelnummer: ASB-ARP39483_P050
Artikelname: UTX Antibody - C-terminal region
Artikelnummer: ASB-ARP39483_P050
Hersteller Artikelnummer: ARP39483_P050
Alternativnummer: ASB-ARP39483_P050-25UL,ASB-ARP39483_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human UTX
Alternative Synonym: UTX, KABUK2, bA386N14.2
UTX is a histone demethylase that specifically demethylates Lys-27 of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 Lys-27. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of Lys-27 of histone H3 is concomitent with methylation of Lys-4 of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 154kDa
NCBI: 7403
UniProt: O15550
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-UTX Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysateKDM6A is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells
Host: Rabbit
Target: KDM6A
Positive control (+): Human Ovary (OV)
Negative control (-): Human liver (LI)
Antibody concentration: 1ug/ml
UTX antibody - middle region (ARP39483_P050) in Human MCF7 using Western Blot