UTX Antibody - C-terminal region
Catalog Number:
ASB-ARP39483_P050
- Images (3)
| Article Name: | UTX Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP39483_P050 |
| Supplier Catalog Number: | ARP39483_P050 |
| Alternative Catalog Number: | ASB-ARP39483_P050-25UL,ASB-ARP39483_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C-terminal region of human UTX |
| Alternative Names: | UTX, KABUK2, bA386N14.2 |
| UTX is a histone demethylase that specifically demethylates Lys-27 of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 Lys-27. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of Lys-27 of histone H3 is concomitent with methylation of Lys-4 of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A. |
|
|
WB Suggested Anti-UTX Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: MCF7 cell lysateKDM6A is strongly supported by BioGPS gene expression data to be expressed in Human MCF7 cells |
|
|
Host: Rabbit Target: KDM6A Positive control (+): Human Ovary (OV) Negative control (-): Human liver (LI) Antibody concentration: 1ug/ml |
|
|
UTX antibody - middle region (ARP39483_P050) in Human MCF7 using Western Blot |
Product Guarantee and Expert Support
