ATXN3 Antibody - N-terminal region
Artikelnummer:
ASB-ARP50507_P050
- Bilder (3)
| Artikelname: | ATXN3 Antibody - N-terminal region |
| Artikelnummer: | ASB-ARP50507_P050 |
| Hersteller Artikelnummer: | ARP50507_P050 |
| Alternativnummer: | ASB-ARP50507_P050-25UL,ASB-ARP50507_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human ATXN3 |
| Alternative Synonym: | AT3, JOS, MJD, ATX3, MJD1, SCA3 |
| Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
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WB Suggested Anti-ATXN3 Antibody Titration: 0.2-1 ug/ml Positive Control: 293T cell lysate |
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Lanes: Lane 1: 2ug hATX3 (isoform2), Josephin domain(1-182) Lane 2: 2ug hATX3 (isoform2), C-terminal truncated Atx3 (1-264) Lane 3: 2ug hATX3 (isoform2) Lane 4: 2ug other protein Primary Antibody Dilution: 1:10,000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:20,000 Gene Name: ATXN3 Submitted by: Dr. Maria Macedo, Instituto de Biologia Molecular e Celular |
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ATXN3 antibody - N-terminal region (ARP50507_P050) in Human 293T using Western Blot |
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