ATXN3 Antibody - N-terminal region

Catalog Number: ASB-ARP50507_P050
Article Name: ATXN3 Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP50507_P050
Supplier Catalog Number: ARP50507_P050
Alternative Catalog Number: ASB-ARP50507_P050-25UL,ASB-ARP50507_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATXN3
Alternative Names: AT3, JOS, MJD, ATX3, MJD1, SCA3
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 41kDa
NCBI: 4287
UniProt: P54252
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-ATXN3 Antibody Titration: 0.2-1 ug/ml
Positive Control: 293T cell lysate
Lanes:
Lane 1: 2ug hATX3 (isoform2), Josephin domain(1-182)
Lane 2: 2ug hATX3 (isoform2), C-terminal truncated Atx3 (1-264)
Lane 3: 2ug hATX3 (isoform2)
Lane 4: 2ug other protein
Primary Antibody Dilution:
1:10,000
Secondary Antibody:
Anti-rabbit HRP
Secondary Antibody Dilution:
1:20,000
Gene Name:
ATXN3
Submitted by:
Dr. Maria Macedo, Instituto de Biologia Molecular e Celular
ATXN3 antibody - N-terminal region (ARP50507_P050) in Human 293T using Western Blot