Sgms1 Antibody - middle region

Artikelnummer: ASB-ARP55476_P050
Artikelname: Sgms1 Antibody - middle region
Artikelnummer: ASB-ARP55476_P050
Hersteller Artikelnummer: ARP55476_P050
Alternativnummer: ASB-ARP55476_P050-25UL,ASB-ARP55476_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Sgms1
Alternative Synonym: SM, Mob, Sms1, Sor1, SMS1b, SMS1g, C80702, Tmem23, AI841905, 9530058O11Rik
Bidirectional lipid cholinephosphotransferase is capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Sgms1 directly and specifically recognizes the choline head group on the substrate. It also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Sgms1 does not function strictly as a SM synthase and suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. Sgms1 may protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 49 kDa
NCBI: 208449
UniProt: Q8VCQ6
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
25 ug of the indicated Mouse tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Peptide is present in 49 kDa, 32 kDa and 25 kDa forms. Protein may be phosphorylated.
25 ug of the indicated Mouse tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Peptide is present in 49 kDa, 32 kDa and 25 kDa forms. Protein may be phosphorylated.
WB Suggested Anti-Sgms1 Antibody
Titration: 1.0 ug/ml
Positive Control: Mouse Muscle
Sgms1 Antibody - middle region (ARP55476_P050) in Mouse Muscle using Western Blot