Sgms1 Antibody - middle region
Catalog Number:
ASB-ARP55476_P050
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| Article Name: | Sgms1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP55476_P050 |
| Supplier Catalog Number: | ARP55476_P050 |
| Alternative Catalog Number: | ASB-ARP55476_P050-25UL,ASB-ARP55476_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of Mouse Sgms1 |
| Alternative Names: | SM, Mob, Sms1, Sor1, SMS1b, SMS1g, C80702, Tmem23, AI841905, 9530058O11Rik |
| Bidirectional lipid cholinephosphotransferase is capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Sgms1 directly and specifically recognizes the choline head group on the substrate. It also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Sgms1 does not function strictly as a SM synthase and suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. Sgms1 may protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide. |
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25 ug of the indicated Mouse tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Peptide is present in 49 kDa, 32 kDa and 25 kDa forms. Protein may be phosphorylated. |
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25 ug of the indicated Mouse tissue extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. Peptide is present in 49 kDa, 32 kDa and 25 kDa forms. Protein may be phosphorylated. |
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WB Suggested Anti-Sgms1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Muscle |
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Sgms1 Antibody - middle region (ARP55476_P050) in Mouse Muscle using Western Blot |
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