CMA1 Antibody - C-terminal region

Artikelnummer: ASB-ARP59991_P050
Artikelname: CMA1 Antibody - C-terminal region
Artikelnummer: ASB-ARP59991_P050
Hersteller Artikelnummer: ARP59991_P050
Alternativnummer: ASB-ARP59991_P050-25UL,ASB-ARP59991_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Bovine, Canine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CMA1
Alternative Synonym: CYH, MCT1, chymase
CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 27kDa
NCBI: 1215
UniProt: P23946
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-CMA1 antibody
Catalog Number: ARP59991
Formalin Fixed Paraffin Embedded Tissue: Human Tonsil
Primary antibody Concentration: 1:100
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20x
Exposure Time: 0.5-2.0sec
WB Suggested Anti-CMA1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysateCMA1 is supported by BioGPS gene expression data to be expressed in COLO205
CMA1 antibody - C-terminal region (ARP59991_P050) in Human COLO205 using Western Blot