Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Alternative Synonym:
ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Lanes: Lane 1: 4ug DRM fraction from MDA-MB-231 Primary Antibody Dilution: 1:1000 Secondary Antibody: Donkey anti-rabbit IgG-HRP Secondary Antibody Dilution: 1:10000 Gene Name: EGFR Submitted by: Katarzyna Augoff, University of Wroclaw EGFR is strongly supported by BioGPS gene expression data to be expressed in Human MDA-MB231 cells
EGFR antibody - middle region (ARP61003_P050) in Human Placenta using Western Blot
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