EGFR Antibody - middle region

Catalog Number: ASB-ARP61003_P050
Article Name: EGFR Antibody - middle region
Biozol Catalog Number: ASB-ARP61003_P050
Supplier Catalog Number: ARP61003_P050
Alternative Catalog Number: ASB-ARP61003_P050-25UL,ASB-ARP61003_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Alternative Names: ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 69kDa
NCBI: 1956
UniProt: P00533
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-EGFR Antibody
Catalog Number: ARP61003_P050
Formalin Fixed Paraffin Embedded Tissue: Human Thyroid Gland Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-EGFR Antibody
Titration: 1.0 ug/ml
Positive Control: Placenta
Lanes:
Lane 1: 4ug DRM fraction from MDA-MB-231
Primary Antibody Dilution:
1:1000
Secondary Antibody:
Donkey anti-rabbit IgG-HRP
Secondary Antibody Dilution:
1:10000
Gene Name:
EGFR
Submitted by:
Katarzyna Augoff, University of Wroclaw
EGFR is strongly supported by BioGPS gene expression data to be expressed in Human MDA-MB231 cells
EGFR antibody - middle region (ARP61003_P050) in Human Placenta using Western Blot