CDK6 Antibody - C-terminal region

Artikelnummer: ASB-AVARP03005_T100
Artikelname: CDK6 Antibody - C-terminal region
Artikelnummer: ASB-AVARP03005_T100
Hersteller Artikelnummer: AVARP03005_T100
Alternativnummer: ASB-AVARP03005_T100-25UL,ASB-AVARP03005_T100-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: WB
Spezies Reaktivität: Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDK6
Alternative Synonym: MCPH12, PLSTIRE
CDK6 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.
Klonalität: Polyclonal
Konzentration: 1.0 mg/ml
Molekulargewicht: 37kDa
NCBI: 1021
UniProt: Q00534
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-CDK6 Antibody
Catalog Number: AVARP03005_T100
Formalin Fixed Paraffin Embedded Tissue: Human Bone Marrow Tissue
Observed Staining: Cytoplasm, Nucleus
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-CDK6 Antibody Titration: 0.625ug/ml
Positive Control: Jurkat cell lysateCDK6 is supported by BioGPS gene expression data to be expressed in Jurkat
CDK6 antibody - C-terminal region (AVARP03005_T100) in Human Jurkat using Western Blot