CDK6 Antibody - C-terminal region
Catalog Number:
ASB-AVARP03005_T100
- Images (3)
| Article Name: | CDK6 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-AVARP03005_T100 |
| Supplier Catalog Number: | AVARP03005_T100 |
| Alternative Catalog Number: | ASB-AVARP03005_T100-25UL,ASB-AVARP03005_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Human, Mouse, Porcine, Rabbit |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of human CDK6 |
| Alternative Names: | MCPH12, PLSTIRE |
| CDK6 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. |
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Rabbit Anti-CDK6 Antibody Catalog Number: AVARP03005_T100 Formalin Fixed Paraffin Embedded Tissue: Human Bone Marrow Tissue Observed Staining: Cytoplasm, Nucleus Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-CDK6 Antibody Titration: 0.625ug/ml Positive Control: Jurkat cell lysateCDK6 is supported by BioGPS gene expression data to be expressed in Jurkat |
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CDK6 antibody - C-terminal region (AVARP03005_T100) in Human Jurkat using Western Blot |
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