WDR77 Antibody

Artikelnummer: ASB-OACA07088
Artikelname: WDR77 Antibody
Artikelnummer: ASB-OACA07088
Hersteller Artikelnummer: OACA07088
Alternativnummer: ASB-OACA07088-100UL,ASB-OACA07088-50UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human Methylosome protein 50 protein (1-260AA)
Konjugation: Unconjugated
Alternative Synonym: androgen receptor cofactor p44,HKMT1069,MEP50,MEP-50,methylosome protein 50,Nbla10071,p44,p44/Mep50,testis tissue sperm-binding protein Li 44a,WD repeat-containing protein 77.
Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones (PubMed:11756452). This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage (PubMed:23071334).
Klonalität: Polyclonal
NCBI: 79084
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human pancreas at dilution 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle at dilution 1:100
All lanes: Methylosome protein 50 antibody at 6ug/ml
Lane 1: Hela whole cell lysate
Lan