WDR77 Antibody
Catalog Number:
ASB-OACA07088
- Images (3)
| Article Name: | WDR77 Antibody |
| Biozol Catalog Number: | ASB-OACA07088 |
| Supplier Catalog Number: | OACA07088 |
| Alternative Catalog Number: | ASB-OACA07088-100UL,ASB-OACA07088-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Methylosome protein 50 protein (1-260AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | androgen receptor cofactor p44,HKMT1069,MEP50,MEP-50,methylosome protein 50,Nbla10071,p44,p44/Mep50,testis tissue sperm-binding protein Li 44a,WD repeat-containing protein 77. |
| Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones (PubMed:11756452). This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage (PubMed:23071334). |
| Clonality: | Polyclonal |
| NCBI: | 79084 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human pancreas at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human skeletal muscle at dilution 1:100 |
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All lanes: Methylosome protein 50 antibody at 6ug/ml Lane 1: Hela whole cell lysate Lan |
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