MEOX1 Antibody
Artikelnummer:
ASB-OACA08341
- Bilder (3)
| Artikelname: | MEOX1 Antibody |
| Artikelnummer: | ASB-OACA08341 |
| Hersteller Artikelnummer: | OACA08341 |
| Alternativnummer: | ASB-OACA08341-100UL,ASB-OACA08341-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant Human Homeobox protein MOX-1 protein (1-254AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | homeobox protein MOX-1,KFS2,Mesenchyme homeobox 1,MOX1. |
| Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. |
| Klonalität: | Polyclonal |
| NCBI: | 4222 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution 1:100 |
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Western blot All lanes: MEOX1 antibody at 3.43ug/ml Lane 1A: Mouse liver tissue |
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