MEOX1 Antibody
Catalog Number:
ASB-OACA08341
- Images (3)
| Article Name: | MEOX1 Antibody |
| Biozol Catalog Number: | ASB-OACA08341 |
| Supplier Catalog Number: | OACA08341 |
| Alternative Catalog Number: | ASB-OACA08341-100UL,ASB-OACA08341-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Homeobox protein MOX-1 protein (1-254AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | homeobox protein MOX-1,KFS2,Mesenchyme homeobox 1,MOX1. |
| Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. |
| Clonality: | Polyclonal |
| NCBI: | 4222 |
| Form: | Liquid |
|
|
Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100 |
|
|
Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution 1:100 |
|
|
Western blot All lanes: MEOX1 antibody at 3.43ug/ml Lane 1A: Mouse liver tissue |
Product Guarantee and Expert Support
