MOCS3 Antibody
Artikelnummer:
ASB-OACA08343
- Bilder (3)
| Artikelname: | MOCS3 Antibody |
| Artikelnummer: | ASB-OACA08343 |
| Hersteller Artikelnummer: | OACA08343 |
| Alternativnummer: | ASB-OACA08343-100UL,ASB-OACA08343-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (271-460AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | adenylyltransferase and sulfurtransferase MOCS3,molybdenum cofactor synthesis protein 3,molybdopterin synthase sulfurylase,MPT synthase sulfurylase,UBA4,UBA4, ubiquitin-activating enzyme E1 homolog,ubiquitin-like modifier activating enzyme 4. |
| Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor, NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. |
| Klonalität: | Polyclonal |
| NCBI: | 27304 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100 |
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Western blot All lanes: MOCS3 antibody at 4.25ug/ml Lane 1A: A549 whole cell lysate |
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