RACGAP1 Antibody

Artikelnummer: ASB-OACA08593
Artikelname: RACGAP1 Antibody
Artikelnummer: ASB-OACA08593
Hersteller Artikelnummer: OACA08593
Alternativnummer: ASB-OACA08593-100UL,ASB-OACA08593-50UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: ELISA, IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human Rac GTPase-activating protein 1 protein (353-632AA)
Konjugation: Unconjugated
Alternative Synonym: CYK4,HsCYK-4,ID-GAP,male germ cell RacGap,MgcRacGAP,protein CYK4 homolog,rac GTPase-activating protein 1.
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.
Klonalität: Polyclonal
NCBI: 29127
Formulierung: Liquid
Immunohistochemistry of paraffin-embedded human thymus tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded humanAtestis tissue at dilution 1:100
Western blot
All lanes: RACGAP1 antibody at 2.68 ug/ml
+Raji whole cell lysate