RACGAP1 Antibody
Catalog Number:
ASB-OACA08593
- Images (3)
| Article Name: | RACGAP1 Antibody |
| Biozol Catalog Number: | ASB-OACA08593 |
| Supplier Catalog Number: | OACA08593 |
| Alternative Catalog Number: | ASB-OACA08593-100UL,ASB-OACA08593-50UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Rac GTPase-activating protein 1 protein (353-632AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | CYK4,HsCYK-4,ID-GAP,male germ cell RacGap,MgcRacGAP,protein CYK4 homolog,rac GTPase-activating protein 1. |
| Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells. |
| Clonality: | Polyclonal |
| NCBI: | 29127 |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human thymus tissue at dilution 1:100 |
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Immunohistochemistry of paraffin-embedded humanAtestis tissue at dilution 1:100 |
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Western blot All lanes: RACGAP1 antibody at 2.68 ug/ml +Raji whole cell lysate |
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