RNF5 Antibody
Artikelnummer:
ASB-OACA08890
- Bilder (3)
| Artikelname: | RNF5 Antibody |
| Artikelnummer: | ASB-OACA08890 |
| Hersteller Artikelnummer: | OACA08890 |
| Alternativnummer: | ASB-OACA08890-100UL,ASB-OACA08890-50UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | ELISA, IHC, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant Human E3 ubiquitin-protein ligase RNF5 protein (1-120AA) |
| Konjugation: | Unconjugated |
| Alternative Synonym: | E3 ubiquitin-protein ligase RNF5,protein G16,ram1 homolog,RING finger protein 5,ring finger protein 5, E3 ubiquitin protein ligase,RING5,RING-type E3 ubiquitin transferase RNF5,RMA1. |
| Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the Lys-63-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the Lys-48-linked polyubiquitination of TMEM173 at Lys-150 leading to its proteasomal degradation, the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses. |
| Klonalität: | Polyclonal |
| NCBI: | 6048 |
| Formulierung: | Liquid |
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Immunohistochemistry of paraffin-embedded human gastric cancer at dilution of 1:100 |
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Immunohistochemistry of paraffin-embedded human liver cancer at dilution of 1:100 |
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Western blot All lanes: RNF5 antibody at 3.08 ug/ml Lane 1: A431 whole cell ly |
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