RNF5 Antibody

Catalog Number: ASB-OACA08890
Article Name: RNF5 Antibody
Biozol Catalog Number: ASB-OACA08890
Supplier Catalog Number: OACA08890
Alternative Catalog Number: ASB-OACA08890-100UL,ASB-OACA08890-50UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: ELISA, IHC, WB
Species Reactivity: Human
Immunogen: Recombinant Human E3 ubiquitin-protein ligase RNF5 protein (1-120AA)
Conjugation: Unconjugated
Alternative Names: E3 ubiquitin-protein ligase RNF5,protein G16,ram1 homolog,RING finger protein 5,ring finger protein 5, E3 ubiquitin protein ligase,RING5,RING-type E3 ubiquitin transferase RNF5,RMA1.
Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the Lys-63-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the Lys-48-linked polyubiquitination of TMEM173 at Lys-150 leading to its proteasomal degradation, the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses.
Clonality: Polyclonal
NCBI: 6048
Form: Liquid
Immunohistochemistry of paraffin-embedded human gastric cancer at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer at dilution of 1:100
Western blot
All lanes: RNF5 antibody at 3.08 ug/ml
Lane 1: A431 whole cell ly