APAF1 Antibody - middle region
Artikelnummer:
ASB-OASG00437
- Bilder (3)
| Artikelname: | APAF1 Antibody - middle region |
| Artikelnummer: | ASB-OASG00437 |
| Hersteller Artikelnummer: | OASG00437 |
| Alternativnummer: | ASB-OASG00437-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the Internal region of human Apaf-1. |
| Alternative Synonym: | CED4, APAF-1 |
| This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. |
| Klonalität: | Polyclonal |
| Konzentration: | 1 mg/ml |
| Molekulargewicht: | 135 kDa |
| NCBI: | 317 |
| Formulierung: | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
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Immunohistochemistry using Human Liver |
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Immunohistochemistry using Human Liver |
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Western Blot using K562 |
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