APAF1 Antibody - middle region
Catalog Number:
ASB-OASG00437
- Images (3)
| Article Name: | APAF1 Antibody - middle region |
| Biozol Catalog Number: | ASB-OASG00437 |
| Supplier Catalog Number: | OASG00437 |
| Alternative Catalog Number: | ASB-OASG00437-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the Internal region of human Apaf-1. |
| Alternative Names: | CED4, APAF-1 |
| This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. |
| Clonality: | Polyclonal |
| Concentration: | 1 mg/ml |
| Molecular Weight: | 135 kDa |
| NCBI: | 317 |
| Form: | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
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Immunohistochemistry using Human Liver |
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Immunohistochemistry using Human Liver |
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Western Blot using K562 |
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