Lysophospholipase 1 (18C9) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE04965
Artikelname: Lysophospholipase 1 (18C9) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE04965
Hersteller Artikelnummer: AMRe04965
Alternativnummer: EKL-AMRE04965-50UL, EKL-AMRE04965-100UL, EKL-AMRE04965-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: APT1, hAPT1, LPL1, LYPLA1, Lysophospholipase 1, LYSOPLA, LysoPLA I,
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity. Acts as a acyl-protein thioesterase (PubMed:19439193, PubMed:20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (PubMed:20418879). Has depalmitoylating activity toward KCNMA1 (PubMed:22399288). Could also depalmitoylate ADRB2 (PubMed:27481942). Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC) (PubMed:19439193). Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso- PI) and lysophosphatidylserine (lyso-PS) (By similarity). Has much higher thioesterase activity than lysophospholipase activity (PubMed:19439193). Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA (PubMed:21393252).
Klonalität: Monoclonal
Molekulargewicht: 25kDa
NCBI: 10434
UniProt: O75608
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: LYPLA1
Application Verdünnung: WB 1:500-1:2000



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