Lysophospholipase 1 (18C9) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE04965
Article Name: Lysophospholipase 1 (18C9) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE04965
Supplier Catalog Number: AMRe04965
Alternative Catalog Number: EKL-AMRE04965-50UL, EKL-AMRE04965-100UL, EKL-AMRE04965-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Alternative Names: APT1, hAPT1, LPL1, LYPLA1, Lysophospholipase 1, LYSOPLA, LysoPLA I,
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity. Acts as a acyl-protein thioesterase (PubMed:19439193, PubMed:20418879). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (PubMed:20418879). Has depalmitoylating activity toward KCNMA1 (PubMed:22399288). Could also depalmitoylate ADRB2 (PubMed:27481942). Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC) (PubMed:19439193). Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso- PI) and lysophosphatidylserine (lyso-PS) (By similarity). Has much higher thioesterase activity than lysophospholipase activity (PubMed:19439193). Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA (PubMed:21393252).
Clonality: Monoclonal
Molecular Weight: 25kDa
NCBI: 10434
UniProt: O75608
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: LYPLA1
Application Dilute: WB 1:500-1:2000



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