Phospho-Chk1 (S280) (9M10) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE05874
Produktübersicht
Artikelname:
Phospho-Chk1 (S280) (9M10) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE05874
Hersteller Artikelnummer:
AMRe05874
Alternativnummer:
EKL-AMRE05874-50UL, EKL-AMRE05874-100UL, EKL-AMRE05874-200UL
Hersteller:
EnkiLife
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Alternative Synonym:
Checkpoint kinase 1, Chek1, Chk1, rad27,
Produktbeschreibung
Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles. Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA (PubMed:11535615, PubMed: 12446774, PubMed: 12399544, PubMed: 14559997, PubMed: 14988723, PubMed: 15311285, PubMed: 15665856, PubMed: 15650047, PubMed: 32357935). May also negatively regulate cell cycle progression during unperturbed cell cycles (PubMed: 11535615, PubMed: 12446774, PubMed: 12399544, PubMed: 14559997, PubMed: 14988723, PubMed: 15311285, PubMed: 15665856, PubMed: 15650047). This regulation is achieved by a number of mechanisms that together help to preserve the integrity of the genome (PubMed: 11535615, PubMed: 12446774, PubMed: 12399544, PubMed: 14559997, PubMed: 14988723, PubMed: 15311285, PubMed: 15665856, PubMed: 15650047). Recognizes the substrate consensus sequence [R-X-X- S/T] (PubMed: 11535615, PubMed: 12446774, PubMed: 12399544, PubMed: 14559997, PubMed: 14988723, PubMed: 15311285, PubMed: 15665856, PubMed: 15650047). Binds to and phosphorylates CDC25A, CDC25B and CDC25C (PubMed: 9278511, PubMed: 12676583, PubMed: 14681206, PubMed:
Produkteigenschaften
Klonalität:
Monoclonal
Molekulargewicht:
54kDa
NCBI:
1111
UniProt:
O14757
Puffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit:
Affinity purification
Formulierung:
Liquid
Target-Kategorie:
CHEK1
Anwendungsbeschreibung
Application Verdünnung:
WB 1:1000-1:5000
