Phospho-Tau (S404) (13R18) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE06034
Artikelname: Phospho-Tau (S404) (13R18) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE06034
Hersteller Artikelnummer: AMRe06034
Alternativnummer: EKL-AMRE06034-50UL, EKL-AMRE06034-100UL, EKL-AMRE06034-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ICC, IF, IHC, WB
Spezies Reaktivität: Human, Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: MAPT, Microtubule-associated protein tau, MTBT1, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity (PubMed:21985311). The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both (PubMed:21985311, PubMed:32961270). Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Klonalität: Monoclonal
Molekulargewicht: 79kDa
NCBI: 4137
UniProt: P10636
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: MAPT
Application Verdünnung: WB 1:500-1:2000,IHC 1:20-1:100,ICC/IF 1:20-1:50,IF-P 1:20-1:50



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