Phospho-Tau (S404) (13R18) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE06034
Article Name: Phospho-Tau (S404) (13R18) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE06034
Supplier Catalog Number: AMRe06034
Alternative Catalog Number: EKL-AMRE06034-50UL, EKL-AMRE06034-100UL, EKL-AMRE06034-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: ICC, IF, IHC, WB
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Alternative Names: MAPT, Microtubule-associated protein tau, MTBT1, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity (PubMed:21985311). The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both (PubMed:21985311, PubMed:32961270). Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Clonality: Monoclonal
Molecular Weight: 79kDa
NCBI: 4137
UniProt: P10636
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: MAPT
Application Dilute: WB 1:500-1:2000,IHC 1:20-1:100,ICC/IF 1:20-1:50,IF-P 1:20-1:50



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