MARK3 (4Z8) Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE13650
Artikelname: MARK3 (4Z8) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE13650
Hersteller Artikelnummer: AMRe13650
Alternativnummer: EKL-AMRE13650-50UL, EKL-AMRE13650-100UL, EKL-AMRE13650-200UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FC, ICC, IP, WB
Spezies Reaktivität: Human, Mouse
Konjugation: Unconjugated
Alternative Synonym: C-TAK1, cTAK1, Emk2, KP78, Mark3, PAR1A,
Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on Ser-216. Serine/threonine-protein kinase (PubMed:23666762). Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Phosphorylates CDC25C on Ser-216. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714).
Klonalität: Monoclonal
Molekulargewicht: 84kDa
NCBI: 4140
UniProt: P27448
Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit: Affinity purification
Formulierung: Liquid
Target-Kategorie: MARK3
Application Verdünnung: WB 1:500-1:2000,ICC/IF 1:50-1:100,FC 1:50-1:100,IP 1:20-1:100



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