MARK3 (4Z8) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE13650
Article Name: MARK3 (4Z8) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE13650
Supplier Catalog Number: AMRe13650
Alternative Catalog Number: EKL-AMRE13650-50UL, EKL-AMRE13650-100UL, EKL-AMRE13650-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: FC, ICC, IP, WB
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Alternative Names: C-TAK1, cTAK1, Emk2, KP78, Mark3, PAR1A,
Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on Ser-216. Serine/threonine-protein kinase (PubMed:23666762). Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762). Phosphorylates CDC25C on Ser-216. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613). Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714).
Clonality: Monoclonal
Molecular Weight: 84kDa
NCBI: 4140
UniProt: P27448
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: MARK3
Application Dilute: WB 1:500-1:2000,ICC/IF 1:50-1:100,FC 1:50-1:100,IP 1:20-1:100



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