Orai1 (11C14) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE15491
Produktübersicht
Artikelname:
Orai1 (11C14) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE15491
Hersteller Artikelnummer:
AMRe15491
Alternativnummer:
EKL-AMRE15491-50UL, EKL-AMRE15491-100UL, EKL-AMRE15491-200UL
Hersteller:
EnkiLife
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Alternative Synonym:
CRACM1, Orai 1, ORAI calcium release activated calcium modulator 1, orai1, ORAT1, Protein orai 1, TMEM142A,
Produktbeschreibung
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT. Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 (PubMed:16582901, PubMed: 16645049, PubMed: 16733527, PubMed: 16766533, PubMed: 16807233, PubMed: 19249086, PubMed: 23307288, PubMed: 24351972, PubMed: 24591628, PubMed: 28219928, PubMed: 20354224, PubMed: 26956484). CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed: 16582901). Plays a prominent role in Ca(2+) influx at the basolateral membrane of mammary epithelial cells independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores. May mediate transepithelial transport of large quantities of Ca(2+) for milk secretion.
Produkteigenschaften
Klonalität:
Monoclonal
Molekulargewicht:
33kDa
NCBI:
84876
UniProt:
Q96D31
Puffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit:
Affinity purification
Formulierung:
Liquid
Target-Kategorie:
ORAI1
Anwendungsbeschreibung
Application Verdünnung:
WB 1:1000-1:5000
