Orai1 (11C14) Rabbit Monoclonal Antibody, Unconjugated
Catalog Number:
EKL-AMRE15491
Product Overview
Article Name:
Orai1 (11C14) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-AMRE15491
Supplier Catalog Number:
AMRe15491
Alternative Catalog Number:
EKL-AMRE15491-50UL, EKL-AMRE15491-100UL, EKL-AMRE15491-200UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human
Conjugation:
Unconjugated
Alternative Names:
CRACM1, Orai 1, ORAI calcium release activated calcium modulator 1, orai1, ORAT1, Protein orai 1, TMEM142A,
Product Description
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT. Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 (PubMed:16582901, PubMed: 16645049, PubMed: 16733527, PubMed: 16766533, PubMed: 16807233, PubMed: 19249086, PubMed: 23307288, PubMed: 24351972, PubMed: 24591628, PubMed: 28219928, PubMed: 20354224, PubMed: 26956484). CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed: 16582901). Plays a prominent role in Ca(2+) influx at the basolateral membrane of mammary epithelial cells independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores. May mediate transepithelial transport of large quantities of Ca(2+) for milk secretion.
Product Properties
Clonality:
Monoclonal
Molecular Weight:
33kDa
NCBI:
84876
UniProt:
Q96D31
Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity:
Affinity purification
Form:
Liquid
Target:
ORAI1
Application Notes
Application Dilute:
WB 1:1000-1:5000
