GUCY2F Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A14242
Product Overview
Article Name:
GUCY2F Rabbit pAb, Unconjugated, Polyclonal
Biozol Catalog Number:
ABB-A14242
Supplier Catalog Number:
A14242
Alternative Catalog Number:
ABB-A14242-20UL,ABB-A14242-100UL,ABB-A14242-500UL,ABB-A14242-1000UL
Manufacturer:
ABclonal
Host:
Rabbit
Category:
Antikörper
Application:
ELISA, WB
Species Reactivity:
Human
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation:
Unconjugated
Alternative Names:
CYGF, GC-F, GUC2F, GUC2DL, RETGC-2, ROS-GC2, GUCY2F
Product Description
The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.
Product Properties
Clonality:
Polyclonal
Molecular Weight:
125kDa
NCBI:
2986
UniProt:
P51841
Purity:
Affinity purification
Sequence:
HSALIGGETQMHLLECAHDLKMTDGTYVFVPYDALLYSLPYKHTPYRVLRNNPKLREAYDAVLTITVESQEKTFYQAFTEAAARGEIPEKLEFDQVSPLFGTIYNSIYFIAQAMNNAMKENGQAGAASLVQHSRNMQFHGFNQLMRTDSNGNGISEYVILDTNLKEWELHSTYTVDMEMELLRFGGTPIHFPGGRPPRADAKCWFAEGKIC
Target:
GUCY2F
Antibody Type:
Primary Antibody
Application Notes
Application Dilute:
WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes:
Cross-Reactivity: Mouse,Rat. ResearchArea: Signal Transduction. Shipping: Ice Bag
Images
Western blot analysis of lysates from mouse eye, using GUCY2F Rabbit pAb (A14242) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.