CHRM3 Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A1602
- Images (1)
| Article Name: | CHRM3 Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A1602 |
| Supplier Catalog Number: | A1602 |
| Alternative Catalog Number: | ABB-A1602-100UL,ABB-A1602-20UL,ABB-A1602-1000UL,ABB-A1602-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | HM3, PBS, EGBRS, CHRM3 |
| The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. |
| Application Dilute: | WB,1:1000 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Signal Transduction,G protein signaling,G-Protein-Coupled ReceptorsGPCR,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease. Shipping: Ice Bag |
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Western blot analysis of lysates from SH-SY5Y cells, using CHRM3 Rabbit pAb (A1602) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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