FGFR1OP Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A17627
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| Article Name: | FGFR1OP Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A17627 |
| Supplier Catalog Number: | A17627 |
| Alternative Catalog Number: | ABB-A17627-100UL,ABB-A17627-20UL,ABB-A17627-1000UL,ABB-A17627-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | FOP, FGFR1OP |
| This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohns disease, Graves disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. |
| Application Dilute: | WB,1:500 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Mouse,Rat. ResearchArea: Cancer,Cell Biology Developmental Biology,Cell Cycle,Centrosome,Growth factors. Shipping: Ice Bag |
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Western blot analysis of various lysates using FGFR1OP Rabbit pAb (A17627) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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