Caspase-1 Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A20470
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| Article Name: | Caspase-1 Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A20470 |
| Supplier Catalog Number: | A20470 |
| Alternative Catalog Number: | ABB-A20470-100UL,ABB-A20470-20UL,ABB-A20470-500UL,ABB-A20470-1000UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Mouse |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | ICE, Il1bc, CASP1 |
| Enables cysteine-type endopeptidase activity. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of interleukin-1 beta production, and protein autoprocessing. Acts upstream of or within several processes, including membrane hyperpolarization, mitochondrial depolarization, and positive regulation of interleukin-1 alpha production. Located in extracellular region. Part of IPAF inflammasome complex. Is expressed in knee joint and metanephros. Orthologous to human CASP1 (caspase 1). |
| Application Dilute: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Mouse. Shipping: Ice Bag |
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Western blot analysis of lysates from Mouse testis, using CASP1 Rabbit pAb (A20470) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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