PPARA Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A24835
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| Article Name: | PPARA Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A24835 |
| Supplier Catalog Number: | A24835 |
| Alternative Catalog Number: | ABB-A24835-100UL,ABB-A24835-20UL,ABB-A24835-1000UL,ABB-A24835-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | PPAR, NR1C1, hPPAR, PPARalpha, PPARA |
| Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. |
| Application Dilute: | WB,1:500 - 1:1000 |
| Application Notes: | Cross-Reactivity: Mouse. ResearchArea: Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Biogenesis,Lipid Metabolism,Nucleotide metabolism,Molecular processes,Cardiovascular,Hypoxia,Lipids,Fatty Acids. Shipping: Ice Bag |
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Western blot analysis of lysates from Mouse kidney usingPPARA Rabbit pAb (A24835) at1:700 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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