NR1D2 Antibody - C-terminal region

Catalog Number: ASB-ARP38568_T100
Article Name: NR1D2 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP38568_T100
Supplier Catalog Number: ARP38568_T100
Alternative Catalog Number: ASB-ARP38568_T100-25UL,ASB-ARP38568_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NR1D2
Alternative Names: RVR, BD73, EAR-1R, REVERBB, REVERBbeta
NR1D2 can interact with NCOA5 coactivator, leading to a strong increase of transcription of target genes. NR1D2 also binds to the sequences 5-AATGTAGGTCA-3 and 5-ATAACTAGGTCA-3 and acts as a potent competitive transcriptional silencer and negative regulator of RORalpha mediated trans-activation. NR1D2 may play different roles in metabolism, inflammation, and circadian cycling in the organ-specific manner in homeostasis.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 65 kDa
NCBI: 9975
UniProt: Q14995
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-NR1D2 Antibody Titration: 0.5ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 1 ug/mL of the antibody was used in this experiment.
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