GLA Antibody - N-terminal region
Catalog Number:
ASB-ARP54296_P050
- Images (3)
| Article Name: | GLA Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP54296_P050 |
| Supplier Catalog Number: | ARP54296_P050 |
| Alternative Catalog Number: | ASB-ARP54296_P050-25UL,ASB-ARP54296_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human GLA |
| Alternative Names: | GALA |
| GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. |
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25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 3 ug/mL of the antibody was used in this experiment. In addition to the canonical 49 kDa isoform, the protein is processed to 45 kDa, and a smaller 23 kDa isoform also contains the peptide sequence. The protein also has several glycosylation sites. |
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WB Suggested Anti-GLA Antibody Titration: 0.2-1 ug/ml Positive Control: Human brain |
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GLA antibody - N-terminal region (ARP54296_P050) in Human Brain using Western Blot |
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