BIN1 (14G10) Rabbit Monoclonal Antibody, Unconjugated

Catalog Number: EKL-AMRE07564
Article Name: BIN1 (14G10) Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-AMRE07564
Supplier Catalog Number: AMRe07564
Alternative Catalog Number: EKL-AMRE07564-50UL, EKL-AMRE07564-100UL, EKL-AMRE07564-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: FC, ICC, IHC, IP, WB
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: AMPH2, Amphiphysin 2, Amphiphysin II, AMPHL, Bin1, Bridging integrator 1, SH3P9,
May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation. Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling (PubMed:24755653). Is a negative regulator of endocytosis (By similarity). Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production (PubMed:27179792). In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates (By similarity). May be involved in the regulation of MYC activity and the control cell proliferation (PubMed:8782822). Has actin bundling activity and stabilizes actin filaments against depolymerization in vitro (PubMed:28893863).
Clonality: Monoclonal
Molecular Weight: 65kDa
NCBI: 274
UniProt: O00499
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Purity: Affinity purification
Form: Liquid
Target: BIN1
Application Dilute: WB 1:1000-1:5000,IHC 1:100-1:500,ICC/IF 1:100-1:200,FC 1:20-1:50,IP 1:20-1:50



* VAT and and shipping costs not included.
Errors and price changes excepted
Availability
ORDER BY EMAIL
Product Guarantee and Expert Support
BIOZOL